PresentacióResum de resultatsMapaLlistaCercaCrèditsEnglish

 

Alzheimer's disease, Stroke, Oxidative stress, Oxidases

Investigador/s Principal/s : Mercedes Unzeta Mercedes.Unzeta@uab.es Departament: BIOQUIMICA Y BIOLOGIA MOLECULAR Centre: FACULTAT DE MEDICINA Institució: UAB (Universitat Autònoma de Barcelona) Membres: 4 Línia de recerca: Neurodegeneració i envelliment Àrees:   Transtorns del Sistema Nerviós Central   Mort neuronal  Paraules clau: ALZHEIMER´S DISEASE, STROKE, OXIDATIVE STRESS, OXIDASES, NEUROPROTECTION, DESIGN NEW MOLECULES, POLYPHENOLS AND DIET AND AGING Publicacions: •Anti-apoptotic effect of MAO B inhibitor PF 9601N [N-(2-propynyl)-2-5-benzyloxy-indolyl, methylamine] is mediated by p53 pathway inhibtion in MPP+ treated SH-SY5Y human dopaminergic cells. Sanz E, Quintana A, Battaglia V, Toninello A , Hidalgo J, Ambrosio S, Valoti M , Marco JL, Tipton KF , Unzeta M J neurochem 2008, Jun 1: 105(6):2404-17 IF 4,50 Q1 ,   •Plasma VAP-1/SSAO activity predicts intracranial hemorrhages and adverse neurological outcopme after tissue plasminogen activator treatment in stroke Hernandez-Guillamon M, Garcia-Bonilla L, Sole M, Sosti V, parés M, Campos M, Ortega-Aznar A, Dominguez C, Rubiea M, Ribó M, Quinatna M, Molina CA, Alvarez-Sabin J, Rosell A, Unzeta M, Montaner J Stroke 2010 Jul 41(7) : 1528-35 IF 5.73 Q1  •P53 phosphoryation is involved in vascular cell death induced by the catalytic activity of membrane-bound SSAO/VAP-1 Sole M, Hernandez-Guillamon M, Boada M, Unzeta M Biochim Biophys Acta 2008 Jun; 1783(6):1085-94 IF 4.89 Q1 ISSN:0167-4889 Pàgina Web del grup