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Developmental Biology

principal investigator : Fernando Giraldez - Cristina Pujades - Berta Alsina fernando.giraldez@upf.edu Department: CEXS-Genetics and Neurosciences Center: Facultat de Ciències de la Salut i de la Vida Institution: Universitat Pompeu Fabra (UPF) Members: 12 Research lines: Development and regeneration of the inner ear. Development of the brainstem Areas:  Development  Keywords: ear development,, hair cell, neurogenesis, rhomboencephalon, morphogenesis, progenitors, cell signaling, deafness, cell lineage, otic placode Publications: NEVES, J., PARADA, C., CHAMIZO, M. and GIRALDEZ, F. (2011) “Jagged1 regulates the restriction of Sox2 expression in the developing chicken inner ear: a mechanism for sensory organ specification”. Development 138: 735-744   SAPÈDE, D. and PUJADES, C. (2010) Hedgehog signaling governs the development of sensory epithelium and its associated innervation in the zebrafish inner ear, J. Neurosc 30: 3612-3623, 2010  RADOSEVIC M, ROBERT-MORENO A, COOLEN M, BALLY-CUIF L, ALSINA B. (2011) Her9 represses neurogenic fate downstream of Tbx1 and retinoic acid signaling in the inner ear. Development. 2011 Feb;138(3):397-408. Notes: Group Web site