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Reinforcing Brain Stimulation (ICSS) and Cognition

principal investigator : Pilar Segura - Ignacio Morgado pilar.segura@uab.es Department: Departament de Psicobiologia i Metodologia de les Ciències de la Salut. Center: Institut de Neurociències Institution: UAB (Universitat Autònoma de Barcelona) Members: 3 Research lines: Enhancing cognitive brain using electrical stimulation to strengthen: behavior, synaptic plasticity and neurogenesis. Areas:  Central Nervous System Disorders   Neuronal death   Cognition   Altres membres a temps total de la UAB: Dra. Laura Aldavert Vera Col·laboració amb el Departament de Biologia Celular, Universitat de Girona (membres a temps parcial): Dra. Gemma Huguet Blanco i Dra. Elisabet Kádár Garcia.  Keywords: Intracranial Self Stimulation (ICSS); Deep brain stimulation (DBS); Memory facilitation; Hippocampus; Amygdala; Two-way active avoidance; Morris water maze; Neurogenesis; Orexines; Arc Publications: Segura-Torres P, Aldavert-Vera L, Gatell-Segura A, Redolar-Ripoll D, Morgado-Bernal I. (2010) Intracranial self-stimulation recovers learning and memory capacity in basolateral amygdala-lesioned rats. Neurobiol. Learn. and Mem. 93: 117-126.   Aldavert-Vera L; Huguet G; Costa-Miserachs D, Pena de Ortiz S; Kádár E; Morgado-Bernal I, Segura-Torres P. (2013) Intracranial self-stimulation facilitates active-avoidance retention and induces expression of c-Fos and Nurr1 in rat brain memory systems. Behav. Brain Res., 250: 46-57.   Kádár E, Huguet G, Aldavert-Vera L, Morgado-Bernal I, Segura-Torres P. (2013) Intracranial self-stimulation upregulates the expression of synaptic plasticity related genes and Arc protein expression in rat hippocampus. Genes, Brain and Behav. 12: 771-779.