Cellular Neurobiology - Neuroinflammation
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principal investigator :
Carme Sola - Josep Saura
carme.sola@iibb.csic.es - josepsaura@ub.edu
Department:
Isquèmia Cerebral i Neurodegeneració (CSIC), Ciències Fisiològiques-I (UB)
Center:
IIBB (CSIC), Facultat de Medicina (UB)
Institution:
CSIC, UB, IDIBAPS
Members: 7
Research lines:
Glial activation as a therapeutic target for neurodegenerative diseases
Areas:
Central Nervous System Disorders
Neuronal death
Glial cells
Keywords:
Glial activation, Neuroinflammation, Microglia, Astrocytes, Neurodegenerative diseases, Therapeutic targets, Immunomodulation, C/EBP, EAE, primary cultures, transcription factors
Publications:
Gresa-Arribas N, Viéitez C, Dentesano G, Serratosa J, Saura J, Solà C.(2012) Modelling neuroinflammation in vitro: a tool to test the potential neuroprotective effect of anti-inflammatory agents. PLoS One 7:e45227.
Dentesano G, Straccia M, Ejarque-Ortiz A, Tusell JM, Serratosa J, Saura J,Solà C. (2012) Inhibition of CD200R1 expression by C/EBP and#946; in reactive microglial cells. J Neuroinflammation 9:165.
Valente T, Straccia M, Gresa-Arribas N, Dentesano G, Tusell JM, Serratosa J, Mancera P, Solà C, Saura J. (2013) CCAAT/enhancer binding protein and#948; regulates glial proinflammatory gene expression. Neurobiol Aging 34:2110-24.
Group Web site
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