Vascular Pharmacology

principal investigator :

Elisabet Vila
ELISABET.VILA@UAB.CAT

Department:

Farmacologia, terapèutica i Toxicologia

Center:

Facultat de Medicina

Institution:

UAB (Universitat Autònoma de Barcelona)

Members: 4

Research lines:

Influence of reactive hyperemia on vascular changes after focal cerebral ischemia in rats:  therapeutic potential of drugs. Study of the influence of age and a high fat diet on vascular remodeling and responses using an experimental model of senescence accelerated mouse (SAMP-8). Influence of I / R on intestinal structure, mechanical and vascular function: potential role of different drugs.

Areas:

 Central Nervous System Disorders   Neurotransmission 

Keywords:

vascular remodelling, ischemia-reperfusion, aging, three-dimensional vascular structure, vascular function

Publications:

- Jiménez-Altayó F, Onetti Y, Heras M, Dantas AP, Vila E (20139 Transient Western-style diet modulates contractile responses to phenylephrine differently in mesenteric arteries from senescence-accelerated prone (SAMP8) and resistant (SAMR1) mice. 35(4):1219-34 

- Martínez-Revelles S, Caracuel L, Márquez-Martín A, Dantas A, Oliver E, D'Ocon P, Vila E.(2012)Increased endothelin-1 vasoconstriction in mesenteric resistance arteries after superior mesenteric ischaemia-reperfusion.Br J Pharmacol. 16:937-50. 

 - Jiménez-Altayó F, Caracuel L, Pérez-Asensio FJ, Martínez-Revelles S, Messeguer A, Planas AM, Vila E.(2009) Participation of oxidative stress on rat middle cerebral artery changes induced by focal cerebral ischemia: beneficial effects of 3,4-dihydro-6-hydroxy-7-methoxy-2,2-dimethyl-1(2H)-benzopyran (CR-6).J Pharmacol Exp Ther. 331:429-36 J Pharmacol Exp Ther. 2009 Nov;331(2):429-36


 

IEC  SCB  INC-UAB  UAB

Institut d'Estudis Catalans. Carrer del Carme 47. 08001 Barcelona.
Telèfon +34 933 248 584. Fax +34 932 701 180. scb@iec.cat

- 2014 -



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