Neuropharmacology Laboratory - NEUROPHAR
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principal investigator :
Rafael Maldonado
Director: rafael.maldonado@upf.edu
Gestor: info.neurophar@upf.edu
Department:
DEPARTAMENT DE CIČNCIES EXPERIMENTALS I DE LA SALUT (PROGRAMA DE GENČTICA I NEUROCIČNCIES)
Center:
FACULTAT DE CIČNCIES DE LA SALUT I DE LA VIDA
Institution:
Universitat Pompeu Fabra (UPF)
Members: 33
Research lines:
1) Identification of new therapeutic targets in the nervous system; 2) Neurochemical basis of addiction induced by opiates, cannabinoids and nicotine, addressing both the physical aspects and the components that motivate repeated consumption of these drugs of abuse. 3) Study of diseases and conditions related to addiction, such as affective disorders, cognitive deficits, chronic pain and disorders of food intake, as well as the possible use of drugs for pharmacological treatment.
Areas:
Central Nervous System Disorders
Signalling
Cognition
Keywords:
Drug addiction, affective disorders, intellectual disabilities, neuropathic pain, feeding disorders, preclinical models, neuropharmacology and psychopharmacology
Publications:
1) Cutando L, Busquets-Garcia A, Puighermanal E, Gomis-González M, Delgado-García JM, Gruart A, Maldonado R, Ozaita A Mechanisms underlying the cerebellar deficits produced by repeated cannabis exposure. Journal of Clinical Investigation, 123(7):2816-31, 2013. PMID: 23934130. Q1 D1 (IF 13.765)
2) Busquets-Garcia A, Gomis-González M, Guegan T, Agustín-Pavón C, Pastor A, Mato S, Pérez-Samartín A, Matute C, de la Torre R, Dierssen M, Maldonado R, Ozaita A. Targeting the endocannabinoid system in the treatment of fragile X syndrome. Nature Medicine, 19(5):603-607, 2013. PMID: 23542787. Q1 D1 (IF 28.054)
3) Vallée M, Vitello S, Bellocchio L, Hébert-Chatelain E, Monlezun S, Martin-Garcia E, Kasanetz F, Baillie GL, Panin F, Cathala A, Roullot-Lacarriere V, Fabre S, Hurst DP, Lynch DL, Shore DM, Deroche-Gamonet V, Spampinato U, Revest JM, Maldonado R, Reggio PH, Ross RA, Marsicano G and Piazza PV Pregnenolone can protect the brain from cannabis intoxication Science, 343(6166):94-98, 2014. PMID: 24385629. Q1 D1 (IF 31.477)
Notes:
Group Web site
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