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principal investigator :
José Aguilera
jose.aguilera@uab.cat
Department:
Institut de Neurociències, Departament de Bioquímica i de Biologia Molecular
Center:
Facultat de Medicina
Institution:
UAB (Universitat Autònoma de Barcelona)
Members: 6
Research lines:
Areas:
Central Nervous System Disorders
Neurotransmission
Signalling
Neuronal death
Glial cells
Cognition
Keywords:
Tetanus toxin, Signal transduction, Neuroprotection, Parkinson disease, Neurotrophins, Lipid rafts, serotonin, neuronal death, Bergmann glia, Amyotrophy Lateral Sclerosis
Publications:
Herrando-Grabulosa M, Casas C, Aguilera J.
The C-terminal domain of tetanus toxin protects motoneurons against acute excitotoxic damage on spinal cord organotypic cultures.
J Neurochem. 2013 ;124(1):36-44. Epub 2012
Cubí R, Candalija A, Matas L.A. , Ortega A. , Gil C. and J. Aguilera.
Tetanus toxin Hc fragment induces the formation of ceramide platforms and protects neuronal cells against oxidative stress.
Plot One 8 (6): e68055, 2013
Chaïb-Oukadour I, Gil C, Rodríguez-Alvarez J, Ortega A, Aguilera J.
Tetanus toxin H(C) fragment reduces neuronal MPP+ toxicity.
Mol Cell Neurosci 2009; 41(3): 297-303
Group Web site
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