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principal investigator :
Matthieu Louis
matthieu.louis_at_crg.eu
Department:
Systems Biology
Center:
Centre for Genomic Regulation
Institution:
Centre for Genomic Regulation (CRG)
Members: 10
Research lines:
The mission of our group is to unravel structure-function relationships between neural circuits, sensory coding and adaptive behaviours. We are interested in understanding how odour tracking comes about in terms of circuit computation. This problem is tackled in the olfactory system of the fruit fly Drosophila melanogaster larva. Our research combines a variety of experimental and computational techniques aiming to define how naturalistic odorant stimuli are encoded and processed in the olfactory system. In particular, we are developing new computational tools to monitor and classify stereotypical behaviours automatically. We are seeking to identify circuits involved in the processing of olfactory information and the making of decisions underlying chemotaxis.
Areas:
Neurotransmission
Cognition
Keywords:
Drosophila melanogaster larva, olfactory system, stereotypical behaviours, circuit computation, chemotaxis, active sensing; sensorimotor integration
Publications:
Gomez-Marin, A., Louis, M.. Multilevel control of run orientation in Drosophila larval chemotaxis. Front Behav Neurosci 8:38-38. 13/02/2014. F.I.: 4.758. [doi:10.3389/fnbeh.2014.00038]
Gomez-Marin, Alex, Louis, Matthieu. Active sensation during orientation behavior in the Drosophila larva: more sense than luck. Curr Opin Neurobiol 22:208-215. 01/04/2012. F.I.: 7.335. [doi:10.1016/j.conb.2011.11.008]
Gomez-Marin, Alex, Stephens, Greg J., Louis, Matthieu. Active sampling and decision making in Drosophila chemotaxis. Nat Commun 2:441-441. 01/08/2011. F.I.: 7.396. [doi:10.1038/ncomms1455]
Group Web site
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