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Memory Unit - Alzheimer's Laboratory

principal investigator : Alberto Lleó Department: NEUROLOGIA/MEMORIA Center: HOSPITAL DE SANT PAU Institution: Hospital de Sant Pau Members: 15 Research lines: Biochemical and neuroimaging biomarkers Genetics of neurodegenerative diseases Molecular bases of dementias Areas:  Central Nervous System Disorders   Neuronal death  Keywords: Alzheimer, dementia, amyloid, CSF, genetics, amyloid imaging, MRI Publications: Fortea J, Vilaplana E, Alcolea D, Carmona-Iragui M, Sánchez-Saudinos MB, Sala I, Antón-Aguirre S, González S, Medrano S, Pegueroles J, Morenas E, Clarimón J, Blesa R, Lleó A; for the Alzheimer's Disease Neuroimaging Initiative. Cerebrospinal fluid and#946;-amyloid and phospho-tau biomarker interactions affecting brain structure in preclinical Alzheimer disease. Ann Neurol. 2014 May 23. doi: 10.1002/ana.24186. [Epub ahead of print]  Dols-Icardo O, García-Redondo A, Rojas-García R, Sánchez-Valle R, Noguera A, Gómez-Tortosa E, Pastor P, Hernández I, Esteban-Pérez J, Suárez-Calvet M, Antón-Aguirre S, Amer G, Ortega-Cubero S, Blesa R, Fortea J, Alcolea D, Capdevila A, Antonell A, Lladó A, Muñoz-Blanco JL, Mora JS, Galán-Dávila L, Rodríguez De Rivera FJ, Lleó A, Clarimón J. Characterization of the repeat expansion size in C9orf72 in amyotrophic lateral sclerosis and frontotemporal dementia. Hum Mol Genet. 2014 Feb 1;23(3):749-54. Pera M, Alcolea D, Sánchez-Valle R, Guardia-Laguarta C, Colom-Cadena M, Badiola N, Suárez-Calvet M, Lladó A, Barrera-Ocampo AA, Sepulveda-Falla D, Blesa R, Molinuevo JL, Clarimón J, Ferrer I, Gelpi E, Lleó A. Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease. Acta Neuropathol. 2013 Feb;125(2):201-13. Group Web site