|  principal investigator : 
                       Reinald Pamplona - Manuel Portero-Otin  manuel.portero@mex.udl.cat
 Department: 
                      Medicina Experimental  Center: 
                      Facultat de Medicina Institution: 
                      Universitat de Lleida-IRBLLEIDA Members: 14 Research lines:  
                      Aging and neurodegeneration Areas: 
                       
                        
                         Central Nervous System Disorders 
                          Neuronal death 
                         
                       Keywords:  
                      ageing, oxidative stress, mitochondria, proteotoxicity, neurodegeneration, amyotrophic lateral sclerosis, metabolomics, lipidomics Publications:
 
                      Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis. Brain. 2007 Dec;130(Pt 12):3111-23. Epub 2007 Aug 23. Life and death: metabolic rate, membrane composition, and life span of animals.Physiol Rev. 2007 Oct;87(4):1175-213.   A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling.EMBO J. 2003 Aug 15;22(16):4103-10.  
                      
                      
                     Group Web site 
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