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Neurodegeneration: Pharmacology and Metabolic Disorders

principal investigator : Francesc X. Sureda - Jaume Folch francesc.sureda@urv.net Department: Unitat de Farmacologia, Dept. Ciències Mediques Bàsiques (Dr. Sureda) Unitat de Bioquímica, Dept. Bioquímica i Biotecnologia Center: Facultat de Medicina i Ciències de la Salut, c./St. Llorenç 21 43201 Reus (Tarragona) Institution: Universitat Rovira i Virgili (URV) Members: 5 Research lines: Metabolic disorders and Alzheimer’s disease risk. NMDA receptor antagonists and neuroprotection. Areas:  Central Nervous System Disorders   Neuronal death   Cognition  Keywords: Alzheimer disease, obesity, NMDA, glutamate, metformin, diabetes, APP, PS1 Publications: 1: Folch J, Pedrós I, Patraca I, Sureda F, Junyent F, Beas-Zarate C, Verdaguer E, Pallàs M, Auladell C, Camins A. Neuroprotective and anti-ageing role of leptin. J Mol Endocrinol. 2012 Oct 10;49(3):R149-56. doi: 10.1530/JME-12-0151. PMID: 22967480.  2: Folch J, Pedrós I, Patraca I, Martínez N, Sureda F, Camins A. Metabolic Basis of Sporadic Alzeimer's Disease. Role of Hormones Related to Energy Metabolism. Curr Pharm Des. 2013;19(38):6739-48. PMID: 23530509.  3: Sureda FX, Junyent F, Verdaguer E, Auladell C, Pelegri C, Vilaplana J, Folch J, Canudas AM, Zarate CB, Pallès M, Camins A. Antiapoptotic drugs: a therapeutic strategy for the prevention of neurodegenerative diseases. Curr Pharm Des. 2011;17(3):230-45. Review. PMID: 21348832.