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Neurobiology Unit

principal investigator : Ramon Trullas ramon.trullas@iibb.csic.es Department: Unitat de Neurobiologia Center: Institut d'Investigacions Biomèdiques de Barcelona Institution: Consell Superior d'Investigacions Científiques (CSIC), CIBERNED Members: 2 Research lines: Molecular mechanisms of neurodegeneration Areas:  Central Nervous System Disorders   Neurotransmission   Neuronal death  Keywords: Neurodegeneration. Alzheimer. Mitochondria. Synaptic plasticity. Publications: Clayton KB, Podlesniy P, Figueiro-Silva J, López-Doménech G, Benitez L, Enguita M, Abad MA, Soriano E, Trullas R. (2012) NP1 Regulates Neuronal Activity-Dependent Accumulation of Bax in Mitochondria and Mitochondrial Dynamics. Journal of Neuroscience. 32(4):1453-66.  López-Doménech G, Serrat R, Mirra S, D'Aniello S, Somorjai I, Abad A, Vitureira N, García-Arumí E, Alonso MT, Rodriguez-Prados M, Burgaya F, Andreu AL, García-Sancho J, Trullas R, Garcia-Fernàndez J, Soriano E. (2012) The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2. Nature Communications. 3:814.  Podlesniy P, Figueiro-Silva J, Llado M, Antonell A, Sanchez-Valle R, Alcolea D, Lleo A, Molinuevo JL, Serra N, Trullas R. (2013). Low CSF concentration of mitochondrial DNA in preclinical Alzheimer’s disease. Annals of Neurology. Jun 22. doi: 10.1002/ana.23955 Group Web site