ForewordData summaryMapListSearchCreditsCatalà

 

Neuropharmacology and Pain

principal investigator : Francisco Ciruela fciruela@ub.edu Department: Unitat de Farmacologia, Departament de Patologia i Terapèutica Experimeltal Center: Facultat de Medicina-Bellvitge Institution: Universitat de Barcelona (UB) Members: 12 Research lines: Oligomerization of G protein-coupled receptors and neurological diseases. Areas:  Central Nervous System Disorders   Neurotransmission   Signalling  Keywords: GPCR, Parkinsons's disease, Pain, Receptor oligomerization, Neuropharmacology, Dopamine, Adenosine, Glutamate, ion channels Publications: 1. Ciruela, F., Vilardaga, J.P. and Fernández-Dueñas. V. (2010). Lighting up multiprotein complexes: lessons from GPCR oligomerization. Trends in Biotechnology 28 (8), 407-415.  2. Vallano, A., Fernández-Dueñas, V., García-Negredo, G., Quijada, M.A., Simón, C.P., Cuffí, M.L., Carbonell, L., Sánchez, S., Arnau, J.M. and Ciruela, F.(2013). Targeting metabotropic glutamate receptror type 5 in Parkinson’s disease: bridging molecular studies and clinical trials. CNS and Neurological Disorders-Drug Targets 12 (8), .  3. Gómez-Soler, M., Fernández-Dueñas, V., Portillo-Salido, E., Pérez, P., Zamanillo, D., Vela, J.M., Burgueño, J. and Ciruela, F. (2014). Predicting the antinociceptive efficacy of sigma-1 receptor ligands by a novel receptor FRET-based biosensor. Journal of Medicinal Chemistry (In press). Group Web site