ForewordData summaryMapListSearchCreditsCatalà

 

Neurometabolic Diseases laboratory

principal investigator : Aurora Pujol apujol@idibell.cat Department: Neurociencies Center: IDIBELL Institution: IDIBELL Members: 16 Research lines: Translational research on hereditary diseases of myelin (leukodystrophy). Areas:  Central Nervous System Disorders   Neuronal death   Glial cells   Grup de recerca consolidat de la Generalitat de Catalunya 2009 (SGR085)  Keywords: leukodystrophies, oxidative stress, mitochondria bioenergetics, axonal degeneration, integration of -omics, biomarkers, translational research, clinical trials Publications: 1-Jone López-Erauskin, Stéphane Fourcade, Jorge Galino, Montserrat Ruiz, Agatha Schlüter, Alba Naudi, Manuel Portero-Otin, Reinald Pamplona, Isidre Ferrer, and Aurora Pujol. Antioxidants Halt Axonal Degeneration in a Mouse Model of X-Adrenoleukodystrophy. Ann Neurol 2011;70:84–92  2-Schlüter A, Espinosa L, Fourcade S, Galino J, López E, Ilieva E, Morató L, Asheuer M, Cook T, McLaren A, Reid J, Kelly F, Bates S, Aubourg P, Galea E, Pujol A. Functional genomic analysis unravels a metabolic-inflammatory interplay in adrenoleukodystrophy. Hum Mol Genet. 2012 Mar 1;21(5):1062-77. 3-Morató L, Galino J, Ruiz M, Calingasan NY, Starkov AA, Dumont M, Naudí A, Martínez JJ, Aubourg P, Portero-Otín M, Pamplona R, Galea E, Beal MF, Ferrer I, Fourcade S, Pujol A. Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy. Brain. 2013 Aug;136(Pt 8):2432-43 Group Web site