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principal investigator :
Jaime Kulisevsky
jkulisevsky@santpau.cat
Department:
Neurologia, Unitat de Trastorns del Movement
Center:
Institut de Recerca de l’Hospital de la Sta Creu i Sant Pau - IIB SANT PAU
Institution:
Institut de Recerca de l’Hospital de la Sta Creu i Sant Pau
Members: 12
Research lines:
Diagnosis and treatment of Parkinson's disease. Cognitive and behavioral disorders in Parkinson's disease. Clinical Study of Essential Tremor and other movement disorders. Translational research: in vitro and in vivo models of parkinsonism for the study of molecular and behavioral disease. Huntington's disease
Areas:
Central Nervous System Disorders
Neurotransmission
Cognition
Generació de nous models de la malaltia de parkinson a través de cultius neuronals derivats de iPSC
Keywords:
Parkinson's disease, Cognitive impairment, 6-OHDA rat model
iPSC-derived dopaminergic neurons, Huntington disease, Essential tremor
Publications:
1. Kulisevsky, J., Role of dopamine in learning and memory: implications for the treatment of cognitive dysfunction in patients with Parkinson's disease. Drugs Aging, 2000. 16(5): p. 365-79.
2. Pagonabarraga, J. and J. Kulisevsky, Cognitive impairment and dementia in Parkinson's disease. Neurobiol Dis, 2012. 46(3): p. 590-6.
3. Perez, V., et al., Effect of the additional noradrenergic neurodegeneration to 6-OHDA-lesioned rats in levodopa-induced dyskinesias and in cognitive disturbances. J Neural Transm, 2009. 116(10): p. 1257-66.
Group Web site
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