Biochemistry

Berg, Jeremy M.; Tymoczko, John L.; Gatto, Jr., Gregory J.; Stryer, Lubert

8 ed.

New York: W.H. Freeman and Company, 2015

p. 323

Glucose 6-phosphate (G-6P)

El context és en una figura. El sinònim no és neològic.

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p. 948

Genes required for galactose utilization in yeast are activated by a transcription factor called GAL4, which recognizes DNA-binding sites with two 5'-CGG-3' sequences on complementary strands separated by 11 base pairs (Figures 32.13).

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p. 184

For example, let us consider the unicellular red alga Galdieria sulphuraria, a remarkable eukaryote that can thrive in extreme environments, including at temperatures up to 56ºC, at pH values between 0 and 4, and in the presence of high concentrations of toxic metals.

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p. 85

Mass spectrometers operate by converting analyte molecules into gaseous, charged forms (gas-phase ions).

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p. 805

TABLE 27.2 Gastrointestinal peptides that regulate food intake

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p. 350

FIGURE 12.15 SDS-acrylamide gel patterns of membrane proteins.

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p. 163

The technique of RNA interference is called gene knockdown, because the expression of the gene is reduced but not eliminated, as is the case with gene knockouts.

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p. 933

Thus, this genetic circuit acts as a switch with two stable states: (1) repressor high, Cro low, corresponding to the lysogenic state, and (2) Cro high, repressor low, corresponding to the lytic state (Figure 31.17).

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p. 1050

Many drugs are not effective in everyone, often because of genetic differences among individuals.

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p. 89

Genomic and proteomic methods are complementary

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p. 18

Examination of genomic variation reveals that, on average, each pair of individuals has a different base in one position per 200 bases; that is, the difference is approximately 0.5%.

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p. 911

The RF interacts with the peptidyl transferase center using a loop containing a highly conserved glycine-glycine-glutamine (GGQ) sequence, with the glutamine methylated on the amide nitrogen atom of the R group.

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p. 304

The first domain, called the gla domain, is rich in xgammax carboxyglutamate residues (abbreviation gla), and the second and third domains are called kringle domains (named after a Danish pastry that they resemble).

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p. 327

Like phosphorylation, GlcNAcylation is reversible, with GlcNAcase catalyzing the removal of the carbohydrate.

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p. 805

Another important gut signal is glucagon-like peptide 1 (GLP-1), a hormone of approximately 30 amino acids in lenght.

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p. 805

Another important gut signal is glucagon-like peptide 1 (GLP-1), a hormone of approximately 30 amino acids in lenght.

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p. 610

Glucose 6-phosphate dehydrogenase deficiency causes a drug-induced hemolytic anemia

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p. 636

Phosphorylase a is the glucose sensor in liver cells, facilitating the switch from degradation to synthesis.

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p. 810

This question is important because a primary function of the pancreas is to respond to the presence of glucose in the blood by secreting insulin, a process referred to as glucose-stimulated insulin secretion (GSIS).

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p. 479

Glutamine phosphoribosyl amidotransferase catalizes this reaction, which is the committed step in purine regulation.

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p. 334

Such proteins, termed glycan-binding proteins, bind specific carbohydrate structures on neighboring cells surfaces.

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p. 911

The RF interacts with the peptidyl transferase center using a loop containing a highly conserved glycine-glycine-glutamine (GGQ) sequence, with the glutamine methylated on the amide nitrogen atom of the R group.

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p. 619

Glycogen Breakdown Requires the Interplay of Several Enzymes

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p. 638

Such accumulations of cytoplasmic glycogen are called glycogen lakes.

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p. 620

Each subunit is compactly folded into an amino-terminal domain (480 residues) containing a glycogen-binding site and a carboxyl-terminal domain (360 residues; Figure 21.5).

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p. 637

Edgar von Gierke described the first glycogen-storage disease in 1929.

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p. 610

Glycolytic intermediates accumulate and are then used by the pentose phosphate pathway to synthesize NADPH and ribose 5-phosphate.

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p. 787

Until recently, high levels of HDL-bound cholesterol ("good cholesterol") relative to LDL-bound cholesterol ("bad cholesterol") were believed to protect against cardiovascular disease.

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p. 402

Because they signal through G proteins, 7TM receptors are often called G-protein-coupled receptors (GPCRs).

El sinònim no és neològic.

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p. 413

The intracellular signaling cascade begins with the binding of Grb2, a key adaptor protein that contains one SH2 domain and two Src homology 3 (SH3) domains.

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p. 810

This question is important because a primary function of the pancreas is to respond to the presence of glucose in the blood by secreting insulin, a process referred to as glucose-stimulated insulin secretion (GSIS).

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p. 632

The synthase is phosphorylated at multiple sites by several protein kinasesxguiollargxnotably, glycogen synthase kinase (GSK), which is under the control of insulin (p. 635), and protein kinase A.

El sinònim no és neològic.

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p. 414

Like the G proteins activated by 7TM receptors, Ras possesses intrinsic GTPase activity.

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p. 413

Because of its effect on Ras, Sos is referred to as a guanine-nucleotide-exchange factor (GEF).

El sinònim no és neològic.

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p. 162-163

The uncleaved single-stranded RNA segment, the guide strand, remains incorporated into the enzyme.

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