Biochemistry

Berg, Jeremy M.; Tymoczko, John L.; Gatto, Jr., Gregory J.; Stryer, Lubert

8 ed.

New York: W.H. Freeman and Company, 2015

p. 378

Ingenious experiments carried out by Alan Hodgkin and Andrew Huxley revealed that action potentials arise from large, transient changes in the permeability of the axon membrane to NA⁺ and K⁺ ions.

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p. 332

I-cell patients are deficient in the N-acetylglucosamine phosphotransferase catalyzing the first step in the addition of the phosphoryl group; the consequence is the mistargeting of eight essential enzymes (Figure 11.28).

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p. 694

The allosteric regulator N-acetylglutamate (NAG) is required for synthetase activity.

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p. 694

This molecule is synthesized by N-acetylglutamate synthase.

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p. 254

For chymostrypsin, such a chromogenic substrate is N-acetyl-L-phenylalanine p-nitrophenyl ester.

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p. 772

This oligosaccharide chain contains at least one acidic sugar, either N-acetylneuraminate or N-glycolylneuraminate.

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p. 668

This reaction is catalyzed by a complex of three membrane-bound proteins: NADH-cytochrome b5 reductase, cytochrome b5, and stearoyl CoA desaturase (Figure 22.31).

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p. 694

The allosteric regulator N-acetylglutamate (NAG) is required for synthetase activity.

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p. 370

These ionic gradients are generated by a specific transport system, an enzyme that is called the Nat⁺-K⁺ pump or the Nat⁺-K⁺ ATPase.

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p. 370

These ionic gradients are generated by a specific transport system, an enzyme that is called the Nat⁺-K⁺ pump or the Nat⁺-K⁺ ATPase.

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p. 1043

Natural products are a valuable source of drugs and drug leads

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p. 237

Natural substrate for chymotrypsin

El context és en una figura.

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p. 12

There is negative free-energy change when and only when the overall entropy of the universe is increased.

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p. 33

Negatively charged amino acids. This set of amino acids contains two with acidic side chains: aspartic acid and glutamic acid (Figure 2.11).

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p. 56

Protein misfolding and aggregation ara associated with some neurological diseases

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p. 155

The development of next-generation sequencing (NGS) platforms has extended this capability to formerly unforeseen levels.

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p. 906

In fact, protein synthesis in bacteria starts with the modified amino acid N-formylmethionine (fMet).

El sinònim no és neològic.

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p. 687

A transcription factor called NF-kB (NF for nuclear factor) initiates the expression of a number of the genes that take part in this response.

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p. 772

This oligosaccharide chain contains at least one acidic sugar, either N-acetylneuraminate or N-glycolylneuraminate.

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p. 155

The development of next-generation sequencing (NGS) platforms has extended this capability to formerly unforeseen levels.

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p. 849

One mechanism, nonhomologous end joining (NHEJ), does not depend on other DNA molecules in the cell.

El sinònim no és neològic.

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p. 326

Sugars in glycoproteins are attached either to the amide nitrogen atom in the side chain of asparagine (termed an N-linkage) or to the oxygen atom in the side chain of serine or threonine (termed an O-linkage), as shown in Figure 11.15.

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p. 330

The O-linked sugar units are fashioned there, and the N-linked sugars, arriving from the ER as a component of a glycoprotein, are modified in many different ways.

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p. 241

The solution came from studies showing that an alkylated porphyrin, N-methylmesoporphyrin, is a potent inhibitor of ferrochelatase (Figure 8.33).

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p. 98

FIGURE 3.43 Basis of NMR spectroscopy.

El sinònim no és neològic.

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p. 99

The basis of this technique is the nuclear Overhauser effect (NOE), an interaction between nuclei that is proportional to the inverse sixth power of the distance between them.

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p. 476

We now turn to the synthesis of glucose from noncarbohydrate precursors, a process called gluconeogenesis.

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p. 439

TABLE 15.4 Noncoenzyme vitamins

El context és en una taula.

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p. 236

Double-reciprocal plots are especially useful for distinguishing between competitive, uncompetitive, and noncompetitive inhibitors.

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p. 174

In contrast, in a nonconservative substitution, an amino acid is replaced by one that is structurally dissimilar.

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p. 342

5. Membranes are noncovalent assemblies. The constituent protein and lipid molecules are held together by many noncovalent interactions, which act cooperatively.

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p. 124

In a nonoverlapping code, ABC designates the first amino acid, DEF the second, and so forth.

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p. 670

Two important classes of compounds that are synthesized by such enzymes are the polyketides and the nonribosomal peptides.

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p. 554-555

In animals, the uncoupling is in brown adipose tissue (BAT), which is specialized tissue for the process of nonshivering thermogenesis.

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p. 388

The acetylcholine receptor is a nonspecific cation channel.

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p. 274

Thus, for EcoRV endonuclease, there is little difference in binding affinity for cognate and nonspecific DNA fragments.

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p. 846

With the addition of each base, there is the possibility than an incorrect base might be incorporated, forming a non-Watson-Crick base pair.

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p. 805

There, one population of neurons expresses appetite-stimulating (orexigenic) peptides, called neuropeptide Y (NPY) and agouti-related peptide (AgRP).

El sinònim no és neològic.

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p. 950

Nuclear hormone receptors regulate transcription by recruiting coactivators to the transcription complex

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p. 99

The basis of this technique is the nuclear Overhauser effect (NOE), an interaction between nuclei that is proportional to the inverse sixth power of the distance between them.

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p. 108

A compound formed by the attachment of a phosphoryl group to C-5' of a nucleoside sugar (the most common site of phosphate esterification) is called a nucleoside 5'-phosphate or a 5'-nucleotide.

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p. 763

Key Steps in Nucleotide Biosynthesis Are Regulated by Feedback Inhibition

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p. 107

Nucleotide triphosphates, nucleosides joinded to three phosphoryl groups, are the monomers--the building blocks--that are linked to form RNA and DNA.

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p. 545

FIGURE 18.28 ATP synthase nucleotide-binding sites are not equivalent.

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